Dr. L. Charles Bailey is a distinguished name in pediatric medicine, recognized for significant contributions to the field. This article compiles a selection of Dr. Bailey’s key publications, demonstrating the breadth and depth of their research across various critical areas within pediatrics. From oncology and gastroenterology to healthcare quality improvement, Dr. Bailey’s work has consistently aimed to advance child health outcomes.
Focus on Pediatric Oncology
Dr. Bailey’s research in pediatric oncology is particularly noteworthy. Their publications shed light on both typical and atypical presentations of leukemia in children, as well as strategies for improving treatment outcomes and reducing mortality.
In a 2016 publication in Pediatric Blood Cancer, Dr. Bailey and colleagues presented a case study on “Atypical Chronic Myeloid Leukemia in Two Pediatric Patients.” This work highlights the complexities of leukemia diagnosis and treatment in young patients, contributing to a deeper understanding of rare disease presentations.
Freedman JL, Desai AV, Bailey LC, Aplenc R, Burnworth B, Zehentner BK, Teachey DT, Wertheim G: Atypical Chronic Myeloid Leukemia in Two Pediatric Patients. Pediatr Blood Cancer 63(1): 156-9, Jan 2016.
Further emphasizing the commitment to improving outcomes in pediatric cancer, Dr. Bailey co-authored a study in Pediatric Blood Cancer in 2014 focusing on factors associated with induction mortality in acute lymphoblastic leukemia. This research identified key patient and hospital factors that can impact survival rates, providing crucial insights for clinical practice and hospital protocols.
Seif AE, Fisher BT, Li Y, Torp K, Rheam DP, Huang YS, Harris T, Shah A, Hall M, Fieldston ES, Kavcic M, Vujkovic M, Bailey LC, Kersun LS, Reilly AF, Rheingold SR, Walker DM, Aplenc R: Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia. Pediatr Blood Cancer 61(5): 846-52, May 2014.
Also in 2014, Bailey and team published in Medical Care detailing the establishment of a large cohort study of pediatric patients with acute lymphoblastic leukemia. This foundational work paved the way for extensive research using healthcare administrative data to understand and improve care for this patient population.
Fisher BT, Harris T, Torp K, Seif AE, Shah A, Huang YV, Bailey LC, Kersun LS, Reilly AF, Rheingold SR, Walker D, Li Y, Aplenc R. Establishment of an 11-Year Cohort of 8733 Pediatric Patients Hospitalized at United States Free-standing Children’s Hospitals With De Novo Acute Lymphoblastic Leukemia From Health Care Administrative Data. Med Care 52(1): e1-6, Jan 2014 Notes: doi: 10.1097/MLR.0b013e31824deff9.
Contributions to Pediatric Gastroenterology
Beyond oncology, Dr. Bailey has made valuable contributions to the field of pediatric gastroenterology. Their research has focused on improving the understanding and management of conditions like ulcerative colitis in children.
A 2015 article in the Journal of Pediatric Gastroenterology and Nutrition investigated the “Feasibility and Validity of the Pediatric Ulcerative Colitis Activity Index in Routine Clinical Practice.” This study assessed the practicality and reliability of a tool used to measure disease activity in pediatric ulcerative colitis, crucial for effective clinical management and research.
Dotson Jennifer L, Crandall Wallace V, Zhang Peixin, Forrest Christopher B, Bailey L Charles, Colletti Richard B, Kappelman Michael D: Feasibility and Validity of the Pediatric Ulcerative Colitis Activity Index in Routine Clinical Practice. Journal of pediatric gastroenterology and nutrition 60(2): 200-4, Feb 2015 Notes: doi: 10.1097/MPG.0000000000000568.
In 2014, Dr. Bailey also contributed to research published in Pediatrics examining the effectiveness of anti-TNFα therapy for Crohn’s disease within a pediatric learning health system. This study provided real-world evidence on the efficacy of this treatment approach for managing Crohn’s disease in children.
Forrest, Christopher; Crandall, Wallace; Bailey, Charles; Zhang,Peixin; Joffe, Marshall; Colletti, Richard; Adler, Jeremy; Baron, Howard;Berman, James; DelRosario, Fernando; Grossman, Andrew; Hoffenberg,Edward; Israel, Esther; Kim, Sandra; Lightdale, Jenifer R.; Margolis,Peter; Marsolo, Keith; Mehta, Devendra; Milov, David; Patel, Ashish;Tung, Jeanne; Kappelman, Michael: Effectiveness of Anti-TNFα for Crohn’s Disease: Research in a Pediatric Learning Health System. Pediatrics Epub, June 2014.
Quality Improvement and Public Health Initiatives
Dr. Bailey’s work extends to quality improvement initiatives and public health concerns affecting children. This includes research on vaccination rates and the impact of early childhood factors on later health outcomes.
A study published in Pediatrics in 2015 detailed a “Quality improvement initiative to increase influenza vaccination in pediatric cancer patients.” This research highlights the importance of proactive measures to protect vulnerable pediatric populations from preventable illnesses like influenza.
Freedman JL, Reilly AF, Powell SC, Bailey LC: Quality improvement initiative to increase influenza vaccination in pediatric cancer patients. Pediatrics 135(2): e540-6, Feb 2015.
Furthermore, Dr. Bailey co-authored a significant study in JAMA Pediatrics in 2014 investigating the “Association of Antibiotics in Infancy With Early Childhood Obesity.” This research explored the potential link between early antibiotic exposure and the development of obesity in young children, raising important questions about antibiotic stewardship and long-term health consequences.
Bailey L Charles, Forrest Christopher B, Zhang Peixin, Richards Thomas M, Livshits Alice, DeRusso Patricia A: Association of Antibiotics in Infancy With Early Childhood Obesity. JAMA pediatrics 168(11): 1063-1069, Nov 2014.
Contributions to Pediatric Health Informatics and Data Standardization
Dr. Bailey’s expertise also encompasses the critical area of pediatric health informatics. Their work has been instrumental in developing systems and terminologies to improve data sharing and research within pediatric healthcare.
In 2014, Dr. Bailey contributed to publications in Academic Pediatrics focusing on “Addressing electronic clinical information in the construction of quality measures” and “Using Medicaid and CHIP claims data to support pediatric quality measurement.” These publications underscore the importance of leveraging electronic health records and administrative data to enhance quality measurement and improve healthcare delivery for children.
Bailey L Charles, Mistry Kamila B, Tinoco Aldo, Earls Marian, Rallins Marjorie C, Hanley Kendra, Christensen Keri, Jones Meredith, Woods Donna: Addressing electronic clinical information in the construction of quality measures. Academic pediatrics 14(5 Suppl): S82-9, Sep-Oct 2014.
Gidengil Courtney, Mangione-Smith Rita, Bailey L Charles, Cawthon Mary Lawrence, McGlynn Elizabeth A, Nakamura Mari M, Schiff Jeffrey, Schuster Mark A, Schneider Eric C: Using Medicaid and CHIP claims data to support pediatric quality measurement: lessons from 3 centers of excellence in measure development. Academic pediatrics 14(5 Suppl): S76-81, Sep-Oct 2014.
Further solidifying this focus, Dr. Bailey co-authored a key article in Pediatrics in 2014 titled “Building a common pediatric research terminology for accelerating child health research.” This seminal work highlights the need for standardized terminologies to facilitate data aggregation and analysis across different pediatric research networks, ultimately accelerating the pace of discovery in child health.
Kahn Michael G, Bailey L Charles, Forrest Christopher B, Padula Michael A, Hirschfeld Steven: Building a common pediatric research terminology for accelerating child health research. Pediatrics 133(3): 516-25, Mar 2014.
Forrest CB, Margolis PA, Bailey LC, Marsolo K, Del Beccaro MA, Finkelstein JA, Milov DE, Vieland VJ, Wolf BA, Yu FB, Kahn MG: PEDSnet: a National Pediatric Learning Health System. J Am Med Inform Assoc May 2014.
Conclusion
Dr. L. Charles Bailey’s extensive publication record demonstrates a profound commitment to advancing pediatric healthcare across a wide spectrum of disciplines. From groundbreaking research in pediatric oncology and gastroenterology to impactful work in quality improvement and health informatics, Dr. Bailey’s contributions have significantly enhanced our understanding of child health and continue to shape the future of pediatric medicine. This compilation of key publications serves as a testament to the dedication and expertise of “Bailey Doctor” in the pursuit of better health outcomes for children.
